Comments on: What is the level of expression of PCA3 by PIN (HG & LG) relative to cancerous tissue? My understanding that all of these categories of tissue “over”express PCA3 but the relative extent by each category is something I cannot determine in my online research. I have had two TRUS biopsies (12 and 18 core), both negative. Have most recent PSA in the 6+ range, normal DRE, but PCA3 result of 86.9. I am due for another biopsy soon. My concern in that the urine testing was skewed by the presence of HGPIN (one core in first bipsy) and LGPIN (several cores in second).

Comments on: What is the level of expression of PCA3 by PIN (HG & LG) relative to cancerous tissue? My understanding that all of these categories of tissue “over”express PCA3 but the relative extent by each category is something I cannot determine in my online research. I have had two TRUS biopsies (12 and 18 core), both negative. Have most recent PSA in the 6+ range, normal DRE, but PCA3 result of 86.9. I am due for another biopsy soon. My concern in that the urine testing was skewed by the presence of HGPIN (one core in first bipsy) and LGPIN (several cores in second). http://prostatecanceradvice.org Prostate Cancer Prognosis, Questions and Answers Tue, 05 Jan 2010 06:25:54 +0000 hourly 1 http://wordpress.org/?v=3.0.3